|Character Profile||List of appearances|
Sandra "Sandy" Roscoe (previously Spencer and Black) was a nurse at Dee Valley University Hospital. She is the wife of the deceased Alan Roscoe and Fraser Black, and the ex-wife of Rick Spencer. She is the mother of Darren Osborne, born to Sandy and Jack Osborne, Joe, Freddie and Ziggy Roscoe, born to Sandy and Alan, as well as Robbie and Jason Roscoe, born to Sandy and Rick.
- Actress Gillian Taylforth decided to quit the role of Sandy in March 2014, her final scenes airing in August 2014. The character returned shortly between December 2014 and departing in January 2015.