2019 was Hollyoaks's twenty-fifth year of production.
- 7th January - Buster Smith's trial for the sexual assault of Brody Hudson in 2006 and Oliver Morgan in 2018.
- 9th January - Buster Smith is acquitted of the charges of sexually assaulting Brody Hudson after Damon Kinsella is revealed to have lied in his statement and in the courtroom.
- 11th January - Buster Smith is sentenced to six years imprisonment for his sexual assault on Oliver Morgan. (Final appearance of the character)
- 12th February - Sylver McQueen is accidentally shot during a scuffle with Liam Donovan.
- 2nd April - Sami Maalik proposes to Liberty Savage, but she rejects after discovering his kiss with Sinead Shelby. Sinead is raped by her husband, Laurie.
- 3rd April - Sami Maalik and Liberty Savage get engaged.
- 11th April - Lily McQueen dies from sepsis after changing her mind at the train station about going on the run with Romeo Quinn. (Final appearance of Lily McQueen)
- 12th April - Romeo Quinn is charged with Mac Nightingale's murder.
- 15th April - Mandy Morgan gives birth to a son via cesarean-section, whom she names Darren Osborne Jr.
- 18th April - Darren Osborne Jr.'s biological father is revealed to be Luke Morgan.
- 26th April - Donna-Marie Quinn is arrested after falsely confessing to Mac Nightingale's murder, having been tricked into it by James Nightingale.
- 1st May - Lily McQueen's funeral takes place.
- 7th May - Damon Kinsella proposes to Maxine Minniver.
- 9th May - Nicole Owen returns to the village after twelve years to visit her nephew, Max. (First appearance of the character since 2007)
- 14th May - Grace Black is accidentally run over by Mercedes McQueen and Liam Donovan after crashing into roadworks.
- 16th May - Harry Thompson is arrested for the hit-and-run on Grace Black.
- 21st May - After being raped being raped by her husband, Laurie, for a second time, Sinead Shelby tells Diane Hutchinson that Laurie has raped her.
- 22nd May - Laurie Shelby is arrested for the rape of his wife, Sinead.
- 24th May - Sinead Shelby is arrested for perverting the course of justice.
- 28th May - After Grace Black breaks up with her, Farrah Maalik leaves the village for Canada. (Final appearance of the character)
- 4th June - Harry Thompson is arrested for the hit-and-run on Grace Black after Sadie Cressington refuses to give him an alibi.
- 11th June - Ste Hay's far-right protest turns into a riot when a large group of far-right extremists begin trashing the village. Several extremists, including Ste, are arrested.
- 17th June - Ste Hay discovers that Jonny Baxter is not his biological brother.
- 18th June - Jack Osborne proposes marriage to Breda McQueen who rejects after discovering that the teens have gone to her pig farm where Louis Loveday is buried.
- 19th June - Breda McQueen proposes to Jack Osborne which he accepts under the belief that the ring belonged to her late father, rather than the deceased Louis Loveday.
- 24th June - Diane Hutchinson visits her son, Finn O'Connor, in prison. (First appearance of the character since 2017)
- 25th June - Laurie Shelby attempts to rape Diane Hutchinson, who manages to escape. However, Laurie catches up to Diane on the front balcony of the high school. She is rescued by Sinead Shelby, who accidentally pushes Laurie over the balcony.
- 26th June - Sinead Shelby is arrested for assault after breaching her bail conditions, but is released after Sally St. Claire provides D.S. Jones CCTV evidence of the attack. Laurie is subsequently arrested for the attempted rape of Diane Hutchinson.
- 27th June - Laurie Shelby is charged with attempted rape.
- 2nd July - Max Owen's birthday party goes disastrously wrong after Mercedes McQueen gets high on drugs, and ends early. Max ends up returning to Greece with Nicole Owen. (Final appearances of Max and Nicole Owen)
- 16th July - Sienna Blake encounters a pair of twins, whom she believes are Sophie and Sebastian Blake. (First appearance of Sebastian since 2018)
- 18th July - Sadie Cressington gives birth to a baby boy, whom she names Isaac, inside The Hutch, delivered by Breda McQueen, with the baby's father, Harry Thompson, the baby's grandfather, Tony Hutchinson, and Tony's friend, Darren Osborne, with her.
- 23rd July - Harry Thompson gets a confession from Mercedes McQueen that she and Liam Donovan hit Grace Black with Harry's car and left her for dead, but on his way to reveal the evidence, Harry is fatally stabbed with a chisel by Breda McQueen. (Final appearance of Harry Thompson)
- 29th July - Sienna Blake locks Nina Robertson in a laundry room and kidnaps the twins Nina is looking after, adamant that they are the twins that Warren Fox had kidnapped in 2017 and 2018.
- 30th July - Maxine Minniver and Damon Kinsella marry. Sienna Blake is talked out of kidnapping the twins after being shown a photo of a man with the twins. However, the man is revealed to be Nina Robertson's brother, as she tells this to Warren Fox, who takes the twins back to Spain. (First appearance of Warren since 2018 and final appearances of Warren and Sebastian Blake)
Real life eventsEdit
- 13th May - Hollyoaks introduces a new title sequence and a revamped theme tune.
- 1st June - Hollyoaks wins best soap, Gregory Finnegan (James Nightingale) wins best actor, Nathan Sussex (Buster Smith) wins best villain and Adam Woodward (Brody Hudson) wins best male dramatic performance at the British Soap Awards.
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